Methadone maintenance therapy promotes initiation of antiretroviral therapy among injection drug users

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Concomitant Drug Use in Patients on Methadone Maintenance Therapy

Background: Methadone maintenance therapy (MMT) is considered as an efficient and effective treatment in management of high risk opioids addiction; although, concomitant use of other drugs may interfere with treatment course and outcome in MMT cases. This study aimed at evaluating patterns of drug use along with methadone based on self reported and urine analysis data in two MMT clinics. Method...

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Changes in sexual and drug-related risk behavior following antiretroviral therapy initiation among HIV-infected injection drug users.

OBJECTIVE To evaluate whether HAART is associated with subsequent sexual and drug-related risk behavior compensation among injection drug users (IDUs). DESIGN A community-based cohort study of 362 HIV-infected IDUs initiating HAART in Baltimore, Maryland. METHODS HAART use and risk behavior was assessed at 8316 biannual study visits (median 23). Using logistic regression with generalized es...

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Self-reported antiretroviral therapy in injection drug users.

CONTEXT The US Public Health Service and the International AIDS Society-USA recently published recommendations for antiretroviral therapy (ART) for persons infected with human immunodeficiency virus (HIV); however, anecdotal evidence suggests that HIV-infected injection drug users (IDUs) may not be receiving optimal care as defined by the recommendations. OBJECTIVE To assess ART use in HIV-in...

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The impact of methadone maintenance therapy on hepatitis C incidence among illicit drug users.

AIMS To determine the relationship between methadone maintenance therapy (MMT) and hepatitis C (HCV) seroconversion among illicit drug users. DESIGN A generalized estimating equation model assuming a binomial distribution and a logit-link function was used to examine for a possible protective effect of MMT use on HCV incidence. SETTING Data from three prospective cohort studies of illicit d...

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Psychosocial determinants of adherence to highly active antiretroviral therapy among injection drug users in Vancouver.

BACKGROUND Sub-optimal adherence to highly active antiretroviral therapy (HAART) among injection drug users (IDUs) is a significant concern. As such, there is an urgent need to identify psychosocial determinants of adherence that can be incorporated into interventions designed to promote optimal adherence. OBJECTIVE To identify psychosocial determinants of adherence to HAART, as well as self-...

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ژورنال

عنوان ژورنال: Addiction

سال: 2010

ISSN: 0965-2140,1360-0443

DOI: 10.1111/j.1360-0443.2010.02905.x